Peptide profile
- Peptide name: AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide)
- Main function: Improves physical performance by stimulating glucose uptake and increasing endurance
- Mechanism of action: Activates AMP-activated protein kinase (AMPK), which improves muscular and cardiovascular endurance
Key features and benefits
- Blood sugar regulation: May contribute to more stable blood sugar levels
- Appetite regulation: No direct impact noted
- Muscle Mass & Endurance: Increases muscle energy and improves endurance
- Weight loss: Stimulates fat burning
- Recovery & Healing: May speed up muscle recovery
- Joint health: May have a positive effect on joints (limited evidence)
- Anti-aging: May support cellular energy and counteract aging
- Libido: No direct impact
- Sleep & mood: No direct impact
Recommended dosage & use
- Daily dose: 10–20 mg
- Administration: Subcutaneous injection (under the skin)
- Timing: Optimal before training for maximum endurance and performance
Instructions for the pen
- Each click = 500 µg
- Dosage example:
- 1 click = 500 µg
- 10 clicks = 5 mg
- 20 clicks = 10 mg
- Adjust the pen by turning the knob (1 mark = 1 unit)
- Inject into the abdomen or front of the thigh
- Wait 10 seconds before removing the needle
- Change injection sites to avoid irritation
Pen information
- One pen contains 100 units of 500 µg
- A 50 mg pen lasts approximately 5 days , depending on daily dose
- Example of unit calculation:
- 1 unit = 500 µg
- 5 units = 2.5 mg
- 10 units = 5 mg
- 20 units = 10 mg
- 30 units = 15 mg
- 40 units = 20 mg
Cycle length
- Recommended use: 15–20 days per cycle
What is AICAR?
AICAR is an experimental peptide that improves glucose metabolism and increases physical endurance. It activates AMPK, an enzyme that regulates glucose and fat metabolism in cells, and increases the production of ATP, the primary energy currency of cells.
Medically, AICAR is used to treat metabolic syndrome, diabetes, and other metabolic-related conditions. In sports, AICAR is used to improve endurance, which prolongs and intensifies training sessions. This is also the reason why AICAR is banned by the World Anti-Doping Agency (WADA).
Benefits of AICAR
- Increases the sensitivity of cells to insulin
- Stimulates mitochondrial production in muscles → increased energy capacity
- Protects cells against oxidative stress and aging
- Anti-inflammatory effects
- Improves cardiovascular function
- Supports nerve cell growth and neurological health
- Helps reduce body fat and improve physical fitness
Clinical studies
- Studies show that AICAR converts fat into energy → weight loss and improved metabolism
- Increased muscle strength, endurance and muscle mass have been documented
- Clinical trials show promising results for metabolism, muscle performance and endurance
Possible side effects
- Headache
- Stomach upset
- Temporary sleep or mood changes (rare)
- Follow dosage instructions carefully to minimize risk
Use in sports
- Improves physical endurance, muscle mass and recovery
- Banned from competitive sports by WADA
- Some endurance athletes use AICAR despite ban
Combination with other peptides
- HGH Fragment 176-191: Increases fat burning
- IGF-1LR3: Promotes muscle mass and recovery
- BPC-157: Supports tissue repair and regeneration
Summary
AICAR is a powerful peptide with the potential to improve endurance, metabolism, and physical performance. Proper use and dosage are crucial for efficacy and safety.
Key points:
- Activates AMPK → improved energy, endurance and metabolism
- Recommended daily dose: 10–20 mg
- Optimal for those looking to improve endurance and metabolic efficiency
Frequently Asked Questions (FAQ)
- What is AICAR?
- A peptide that affects cell metabolism and increases endurance through AMPK activation.
- Who can benefit from AICAR?
- Those who want to improve endurance, metabolism or physical performance. Also interesting in medical research for diabetes and metabolic syndrome.
- Are there any side effects?
- Common side effects include headaches, stomach upset, or changes in sleep/mood. Often mild and transient.
- How long before results are visible?
- Some notice improved stamina and energy within a few weeks; others may need longer.
- Can AICAR be used for weight loss?
- Can stimulate fat metabolism, but is not a stand-alone weight loss solution. Diet and exercise are essential.
- How do you start using it?
- Start with the lowest recommended dose and gradually increase if needed.
Why choose Nordic Peptides?
Nordic Peptides offers AICAR of the highest purity and quality in Europe. All peptides are produced with strict quality controls for maximum efficacy and safety.










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